S. Boulardii
For Dogs & Cats
S. Boulardii+ is a veterinarian-formulated probiotic supplement featuring Saccharomyces boulardii — a probiotic yeast, not a bacterium — at 10 billion CFU for large dogs, alongside inulin from Jerusalem artichoke as a prebiotic to support its activity in the gut.
Unlike bacterial probiotics that are largely inactivated during antibiotic treatment and degrade rapidly when exposed to heat and moisture, S. boulardii's yeast cell wall provides inherent shelf stability and full efficacy alongside antibiotics — making it the probiotic of choice for gut health support during and after periods of disruption.
Designed to Support:
- Pets requiring gut support during or following antibiotic therapy
- Normal stool quality, consistency, and frequency
- Gut microbiome diversity and stability
- Healthy gut barrier function and normal intestinal permeability
- Healthy immune function through active support at the gut-immune interface
- Healthy skin in pets with seasonal, environmental, or food-related sensitivities
Saccharomyces boulardii
Inulin (Jerusalem Artichoke)
A gut-friendly probiotic yeast that is uniquely resistant to antibiotics. Unlike bacterial probiotics, which are largely inactivated during antibiotic treatment, S. boulardii maintains full efficacy when given alongside antibiotics to support normal gut function and microbiome stability.
A soluble prebiotic fiber with immunomodulatory properties that feeds and supports the growth of beneficial gut bacteria. Studied in dogs for its ability to support normal digestion, beneficial gut flora, and gut microbiome diversity and stability.
CFU: The Number That Actually Matters
Not all probiotic supplements deliver a meaningful dose. CFU — colony-forming units — is the measure of how many viable probiotic organisms are in each serving, and it is the single most important number on a probiotic label.
Most pet probiotic products contain anywhere from 100,000 to a few million CFU. At those levels, the dose is unlikely to have any meaningful impact on gut function, regardless of the strain.
The clinical research on S. boulardii — the studies that established its efficacy for normal stool quality, gut barrier function, and microbiome support — used doses in the billions, not the millions. Any product dosed below that is a fundamentally different product operating below the threshold where the research-backed benefits have been demonstrated.
Shelf stability is the other half of the equation.
Bacterial probiotics are notoriously fragile. Exposure to moisture, air, and ambient temperature degrades viable CFU counts significantly over time — which is why many bacterial probiotic products require refrigeration, and why a product with 1 billion CFU at manufacture may deliver a fraction of that by the time it reaches your pet.
S. boulardii as a yeast is inherently more shelf-stable than bacterial strains. Its cell wall structure provides natural resistance to moisture and oxygen exposure, maintaining viable CFU counts through normal storage conditions without refrigeration.
Product Ingredient Details
Saccharomyces boulardii
- A probiotic yeast — not a bacterium — making it uniquely resistant to antibiotics and medications that disrupt bacterial probiotic strains
- Unlike bacterial probiotics, which are largely inactivated during antibiotic treatment, S. boulardii maintains full efficacy when given concurrently with antibiotic therapy
- Survives GI transit as a yeast, reaching the lower GI tract where its benefits are most relevant
- Supports healthy gut barrier function and normal intestinal permeability
- Supports gut microbiome diversity by feeding beneficial bacteria
- Supports normal stool quality and consistency
- Supports healthy immune function through its activity at the gut-immune interface
- Supports gut microbiome diversity and helps restore beneficial microbial populations following dysbiosis (imbalance of gut bacteria)
- Supports healthy skin
Inulin (Jerusalem Artichoke)
- A soluble prebiotic fiber that selectively feeds beneficial gut bacteria to support microbiome diversity and stability
- Studies in dogs have demonstrated support for normal digestion and favorable shifts in beneficial gut flora with Jerusalem artichoke-sourced inulin
- Carries immunomodulatory properties that complement the immune-supporting activity of S. boulardii
- Supports healthy gut barrier function
- Supports normal stool quality
Every ingredient in this formula is backed by peer-reviewed research. Explore the science and review our reference sources here.
The Daily Eats Difference
Quality First
Made in the same certified GMP facilities used for human supplements — because your pet's health deserves that standard too.
Safety Prioritized
Ingredients are tested in raw and finished form to screen for contaminants and confirm what's on the label is actually in the bottle.
Evidence Based
Every component of the formula earns its place through peer-reviewed research, so each ingredient is there because it works.
Dosing Matters
We formulate at levels shown to be effective — because listing an ingredient at an amount too low to matter is just marketing.