Veterinarian Formulated
Clean Ingredients
Research-Backed Doses
Joint Advanced
3.7 oz (105 g)
$32.40
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$32.40
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Joint Advanced
For Dogs & Cats
Joint Advanced is a veterinarian-formulated supplement built around two clinically studied branded ingredients — CurcuVet™ phytosomal curcumin and GlycOmega™ flash-dried green-lipped mussel — alongside a comprehensive spectrum of joint support compounds: glucosamine, MSM, chondroitin, hyaluronic acid, Boswellia, Corydalis, and green tea extract.
Formulated for dogs with elevated joint support needs — working and competitive dogs, geriatric dogs, and those requiring more intensive daily support — Joint Advanced addresses joint comfort, mobility, and a normal inflammatory response.
Designed to Support:
- Pets with elevated, complex, or acute joint and connective tissue support needs, including geriatric dogs and cats, and competitive or working dogs
- Joint comfort and mobility through all life stages
- A normal inflammatory response in joint tissue, supported through multiple complementary botanical and nutritional pathways
- Cartilage integrity and connective tissue health
- Normal joint fluid viscosity and lubrication
- Healthy collagen production and tissue integrity
- Antioxidant protection in joint tissue from multiple botanical sources
CurcuVET®
Phytosomal Curcumin
GlycOmega™
Green-Lipped Mussel
Boswellia & Corydalis
Herbal Extracts
Green Tea Extract
A patented curcumin extract complexed with phospholipids for 29x greater bioavailability, shown to support a normal inflammatory response and healthy liver and gastrointestinal function in dogs and cats.
Flash-dried to preserve all bioactive proteins and omega-3 lipids, providing natural glucosamine, chondroitin, hyaluronic acid, EPA and DHA, and all 21 amino acids — a whole-food source of critical joint nutrients.
Boswellia serrata's boswellic acids target the 5-lipoxygenase cascade to support a normal inflammatory response in joint tissue, while Corydalis alkaloids provide complementary support for everyday comfort.
Concentrated in EGCG, green tea's polyphenols deliver targeted antioxidant protection to joint cartilage and surrounding tissue, helping neutralize the oxidative stress that accompanies normal joint activity.
The Branded Ingredient Difference: CurcuVet™
Standard turmeric extract and curcumin supplements share a well-documented limitation:
raw curcumin is poorly absorbed through the GI tract
Without a delivery system designed to overcome this, most passes through without reaching systemic circulation in meaningful concentrations — regardless of dose.
CurcuVet™ solves this through phytosomal delivery: curcumin is bound to phosphatidylcholine using a patented process, forming a fat-soluble complex that dramatically increases absorption through the intestinal wall.
The result is a clinically distinct ingredient.
- Phytosomal curcumin achieves significantly higher plasma concentrations than equivalent doses of standard curcumin extract in comparative bioavailability studies
- CurcuVet™ has been studied specifically in dogs, with published data supporting its use for joint comfort and a normal inflammatory response in joint tissue
- The patented Phytosome® technology (Indena®) is the same platform behind multiple human clinical-grade botanical extracts — rigorously adapted here for veterinary application
A turmeric capsule and CurcuVet™ are not interchangeable. The delivery system is the difference between an ingredient that reaches the target tissue and one that doesn't.
Product Ingredient Details
CurcuVet™ Phytosomal Curcumin
- CurcuVet™ uses phytosome technology — curcumin bound to phospholipids — enabling significantly higher absorption than standard curcumin extracts, with studies demonstrating approximately 29 times greater bioavailability.
- The phospholipid complex also helps mask the natural curry taste, making it significantly more palatable.
- Supports a healthy balance of inflammatory cytokines and a normal inflammatory response in dogs and cats.
- Provides antioxidant support through elevation of the body's natural glutathione system.
- Supports healthy liver and gastrointestinal function and the body's natural detoxification processes.
- Supports normal muscle recovery following activity.
GlycOmega™ Green-Lipped Mussel
- Unlike many other Perna products, GlycOmega™ is produced using an advanced flash-dry process to ensure all bioactive proteins and omega-3 lipids are retained. Typical air-drying processes reduce essential nutrients and bioactivity, whereas the flash-dry process preserves all of them.
- Naturally provides glucosamine, chondroitin sulfate, and hyaluronic acid alongside EPA and DHA omega-3 fatty acids that support a normal inflammatory response in joint tissue.
- Contains all 21 essential and non-essential amino acids — the building blocks of bodily tissue including bones, cartilage, skin, organs, and glandular tissues.
- Provides natural antioxidants to support against free radicals and normal cellular function.
- Good source of minerals important nutrients for bone and cartilage health.
Glucosamine
- A critical building block of glycosaminoglycans (GAGs) — the structural components of cartilage matrix, synovial fluid, ligaments, and tendons.
- Supports chondrocyte synthesis of proteoglycans and collagen, helping to maintain the structural integrity of joint tissue.
- Oral supplementation in dogs and cats has been shown to support joint comfort and mobility, with studies demonstrating improved lameness scores and no adverse effects with long-term administration.
MSM (Methylsulfonylmethane)
- An organic sulfur compound naturally found in the body, providing a highly bioavailable source of sulfur — an essential building block of the amino acids that form cartilage, connective tissue, and joint structures.
- An important part of healthy collagen production, supporting the structural integrity of joints, ligaments, and tendons.
- Supports the production of immunoglobulins that contribute to healthy immune system function.
- Has antioxidant properties and supports a normal inflammatory response in joint tissue.
Chondroitin
- The predominant structural component of articular cartilage, also naturally present in tendons, bones, and vertebral discs.
- Helps maintain cartilage health by absorbing fluid into the connective tissue, supporting normal shock absorption.
- Has been shown to support cartilage integrity by slowing down cartilage degradation.
- Provides the nutritional building blocks for the body to produce and maintain healthy cartilage.
- Has been showin in double-blind clinical trials in dogs to significantly improve joint comfort and mobility.
Boswellia Extract
- Boswellia's active boswellic acids target the 5-lipoxygenase (5-LOX) enzyme pathway — a key driver of the body's inflammatory response — to support normal inflammation levels in joint and connective tissue
- This mechanism is distinct from COX-pathway inhibitors, making Boswellia a complementary botanical option for long-term joint health support
- In a peer-reviewed canine study, dogs receiving Boswellia resin supplementation showed measurable improvements in overall condition, gait, and comfort
Corydalis
- Contains active alkaloids including DHCB (dehydrocorybulbine) and tetrahydropalmatine, which work through opioid and dopamine receptor pathways to support healthy everyday comfort
- Provides a botanical approach to comfort support that works through mechanisms distinct from both COX-pathway inhibitors and the 5-LOX pathway targeted by Boswellia
- Long used in Traditional Chinese Veterinary Medicine for musculoskeletal support, with growing interest in its active alkaloid mechanisms in modern veterinary research
Green Tea Extract
- Contains active alkaloids including DHCB (dehydrocorybulbine) and tetrahydropalmatine, which work through opioid and dopamine receptor pathways to support healthy everyday comfort
- Provides a botanical approach to comfort support that works through mechanisms distinct from both COX-pathway inhibitors and the 5-LOX pathway targeted by Boswellia
- Long used in Traditional Chinese Veterinary Medicine for musculoskeletal support, with growing interest in its active alkaloid mechanisms in modern veterinary research
Hyaluronic Acid
- A naturally occurring glycosaminoglycan and key structural component of synovial fluid, where it contributes to the viscoelastic properties essential for joint lubrication and shock absorption
- Supports the maintenance of normal synovial fluid viscosity, helping cushion joint surfaces during movement and reducing friction between articulating cartilage surfaces
- Works synergistically with glucosamine and chondroitin to support the overall glycosaminoglycan matrix of joint cartilage
- Peer-reviewed research supports oral hyaluronic acid's role in promoting joint comfort and mobility in dogs
- Provides targeted synovial fluid support that complements the structural and botanical ingredients throughout the formula
Every ingredient in this formula is backed by peer-reviewed research. Explore the science and review our reference sources here.
The Daily Eats Difference
Quality First
Made in the same certified GMP facilities used for human supplements — because your pet's health deserves that standard too.
Safety Prioritized
Ingredients are tested in raw and finished form to screen for contaminants and confirm what's on the label is actually in the bottle.
Evidence Based
Every component of the formula earns its place through peer-reviewed research, so each ingredient is there because it works.
Dosing Matters
We formulate at levels shown to be effective — because listing an ingredient at an amount too low to matter is just marketing.